van Dieren A., Schwarzenbacher R.E., Sonnewald S., Bittner A., and Vothknecht U.C. (2024)
Analysis of abiotic and biotic stress-induced Ca²⁺ transients in the crop species Solanum tuberosum
Scientific Reports 14, 27625; doi.org/10.1038/s41598-024-79134-3

Abdelhakim L.O.A., Pleskačová B., Rodriguez-Granados N.Y., Sasidharan R., Perez-Borroto L.S., Sonnewald S., Gruden K., Vothknecht U.C., Teige M., and Panzarová K. (2024)
High Throughput Image-Based Phenotyping for Determining Morphological and Physiological Responses to Single and Combined Stresses in Potato
J. Vis. Exp. 208; doi:10.3791/66255

Bleker C., Ramšak Z., Bittner A., Podpečan V., Zagorščak M., Wurzinger B., Baebler Š., Petek M., Križnik M., van Dieren A., Gruber J., Afjehi-Sadat L., Županič A., Teige M., Vothknecht U.C., Gruden K. (2024)
Stress Knowledge Map: A knowledge graph resource for systems biology analysis of plant stress responses
Plant Communications 5 (6), 100920; doi.org/10.1016/j.xplc.2024.100920

Bhattacharyya S., Giridhar M., Meier B., Peiter E., Vothknecht U.C. and Chigri F. (2023)
Global transcriptome profiling reveals root-and leaf-specific responses of barley (Hordeum vulgare L.) to H₂O₂
Frontiers in Plant Science; doi.org/10.3389/fpls.2023.1223778

Corti F., Festa M., Stein F., Stevanato P., Siroka J., Navazio L., Vothknecht U.C., Alboresi A., Novák O., Formentin E., Szabò I. (2023)
Comparative analysis of wild-type and chloroplast MCU-deficient plants reveals multiple consequences of chloroplast calcium handling under drought stress
Frontiers in Plant Science; doi.org/10.3389/fpls.2023.1228060

Bittner A., Cieśla A., Gruden K., Lukan T., Mahmud S., Teige M., Vothknecht U.C., Wurzinger B. (2022)
Organelles and phytohormones – a network of interactions in plant stress responses.
Journal of Experimental Botany 21, 7165–7181; https://doi.org/10.1093/jxb/erac384

Giridhar M., Meier B., Imani J., Kogel K., Peiter E., Vothknecht U.C. and Chigri F. (2022)
Comparative analysis of stress-induced calcium signals in the crop species barley and the model plant Arabidopsis thaliana.
BMC Plant Biology 22, 447; doi.org/10.1186/s12870-022-03820-5

Mahmud S., Ullah C., Kortz A., Bhattacharyya S., Yu P., Gershenzon J. and Vothknecht U.C. (2022)
Constitutive expression of JASMONATE RESISTANT 1 induces molecular changes that prime the plants to better withstand drought.
Plant, Cell & Environment 45, 2906-2922; doi/10.1111/pce.14402

Cortese E., Moscatiello R., Pettiti F., Carraretto L., Baldan B., Frigerio L., Vothknecht U.C., Szabo I., De Stefani D., Brini M., and Navazio L. (2021)
Monitoring calcium handling by the plant endoplasmic reticulum with a low-Ca²⁺-affinity targeted aequorin reporter.
The Plant Journal 109, 1014-1027; doi.org/10.1111/tpj.15610

Pirayesh N., Giridhar M., Ben Khedher A., Vothknecht U.C. and Chigri F. (2021)
Organellar Calcium Signaling in Plants: An Update.
BBA Molecular Cell Research 1868, 118948; doi.org/10.1016/j.bbamcr.2021.118948

Ugalde J., Fuchs P., Nietzel T., Cutolo E., Homagk M., Vothknecht U.C., Holuigue U.C., Schwarzländer M., Müller-Schüssele S. and Meyer A. (2021)
Chloroplast-derived photo-oxidative stress causes changes in H₂O₂ and E_GSH in other subcellular compartments.
Plant Physiology 186, 125–141; doi.org/10.1093/plphys/kiaa095

Vothknecht U.C. and Szabo I. (2020)
Channels and transporters for inorganic ions in plant mitochondria: prediction and facts.
Mitochondrion 35, 224-233; doi.org/10.1016/j.mito.2020.05.007

Cutolo E., Parvin N., Ruge H., Pirayesh N., Roustan V., Weckwerth W., Teige M., Grieco M., Larosa V. and Vothknecht U.C. (2019)
The High Light Response in Arabidopsis Requires the Calcium Sensor Protein CAS, a Target of STN7- and STN8-Mediated Phosphorylation.
Frontiers in Plant Science; doi.org/10.3389/fpls.2019.00974

Teardo E., Carraretto L., Moscatiello R., Cortese E., Vicario M., Festa M., Maso L., De Bortoli S., Calì T., Vothknecht U.C., Formentin E., Cendron L., Navazio L. and Ildikò Szabò (2019)
A chloroplast-localized mitochondrial calcium uniporter transduces osmotic stress in Arabidopsis.
Nature Plants 5, 581–588; doi: 10.1038/s41477-019-0434-8

Walter J., Selim K.A., Leganés F., Fernández-Piñas F., Vothknecht U.C., Forchhammer K., Aro E.-M. and Gollan P. (2019)
A novel Ca²⁺-binding protein influences photosynthetic electron transport in Anabaena sp. PCC 7120.
BBA - Bioenergetics 1860, 519-532; doi:10.1016/j.bbabio.2019.04.007

Sello S., Moscatiello R., Mehlmer N., Leonardelli M., Carraretto L., Cortese E., Zanella F.G., Baldan B., Szabò I., Vothknecht U.C.* and Navazio L.* (2018)
Chloroplast Ca²⁺ Fluxes into and across Thylakoids Revealed by Thylakoid-Targeted Aequorin Probes.
Plant Physiology 177, 38-51; doi.org/10.1104/pp.18.00027
*corresponding authors

Pasquini M., Fermani S., Tedesco D., Sciabolini C., Crozet P., Naldi M., Henri J., Vothknecht U.C., Bertucci C., Lemaire S.D., Zaffagnini M. and Francia F. (2017)
Structural basis for the magnesium-dependent activation of transketolase from Chlamydomonas reinhardtii.
BBA - General Subjects 1861, 2132-2145; doi.org/10.1016/j.bbagen.2017.05.021

Parvin N., Carrie C., Pabst I., Läßer A., Laha D., Paul M., Geigenberger P., Heermann R., Jung K., Vothknecht U.C. and Chigri F. (2017)
TOM9.2 Is a calmodulin binding protein critical for TOM complex assembly but not for mitochondrial protein import in Arabidopsis thaliana.
Molecular Plant 10, 575-589; doi.org/10.1016/j.molp.2016.12.012

Ruge H., Flosdorff S., Ebersberger I., Chigri F. and Vothknecht U.C. (2016)
The calmodulin-like proteins AtCML4 and AtCML5 are single-pass membrane proteins targeted to the endomembrane system by an N-terminal signal-anchor sequence.
Journal of Experimental Botany 67, 3985-3996; doi.org/10.1093/jxb/erw101

Sello S., Perotto J., Carraretto L., Szabò I., Vothknecht U.C. and Navazio L. (2016)
Dissecting stimulus-specific Ca²⁺ signals in amyloplasts and chloroplasts of Arabidopsis thaliana cell suspension cultures.
Journal of Experimental Botany 67, 3965-3974; doi.org/10.1093/jxb/erw038

Lorenz A., Lorenz M., Vothknecht U.C., Niopek-Witz S., Neuhaus E.H. and Haferkamp I. (2015)
In vitro analyses of mitochondrial ATP/phosphate carriers from Arabidopsis thaliana revealed unexpected Ca²⁺-effects.
BMC Plant Biology 15, 238-254; doi.org/10.1186/s12870-015-0616-0

Rocha A.G., Mehlmer N., Stael S., Mair A., Parvin N., Chigri F., Teige M. and Vothknecht U.C. (2014)
Phosphorylation of Arabidopsis transketolase at Ser-428 provides a potential paradigm for metabolic control of chloroplast carbon metabolism.
Biochemical Journal 458, 313-322; doi.org/10.1042/BJ20130631

Rocha A.G. and Vothknecht U.C. (2013)
Identification of CP12 as a novel calcium-binding protein in chloroplasts.
Plants 2, 530-540; doi.org/10.3390/plants2030530

*Dolze E., *Chigri F., Hoewing T., Hierl G., Isono E., Vothknecht U.C. and Gietl C. (2013)
Calmodulin-like protein AtCML3 mediates dimerization of peroxisomal processing protease AtDEG15 and contributes to normal peroxisome metabolism.
Plant Molecular Biology 83, 607–624; doi.org/10.1007/s11103-013-0112-6
*both authors contributed equally

Zhang L., Kato Y., Otters S., Vothknecht U.C. and Sakamoto W. (2012)
Essential role of VIPP1 in chloroplast envelope maintenance in Arabidopsis.
Plant Cell 24, 3695-3707 (abstract)

Otters S., Braun P., Huber J., Wanner G., Vothknecht U.C. and Chigri F. (2012)
The first alpha-helical domain of the Vesicle Inducing Protein in Plastids 1 promotes oligomerization and lipid binding.
Planta 237, 529-540 (abstract)

Chigri F., Fuchs M., Otters S. and Vothknecht U.C. (2012)
Thylakoid Membrane Formation: Vipp1 and more.
Endocytobiosis and Cell Research 23, 6-10 (abstract)

Hierl G., Vothknecht U.C. and Gietl C. (2012)
Programmed cell death in Ricinus and Arabidopsis: The function of KDEL cysteine peptidases in development.
Physiologia Plantarum 145, 103-113 (abstract)

Rocha A.G and Vothknecht U.C. (2012)
The role of calcium in chloroplasts - an intriguing and unresolved puzzle.
Protoplasma 249 (4), 57-966 (abstract)

Bayer R.G, Stael S., Rocha A.G., Mair A., Vothknecht U.C. and Teige M. (2012)
Chloroplast localised protein kinases – a step forward towards a complete inventory.
Journal of Experimental Botany 63 (4), 1713-1723 (abstract)

Mehlmer N., Parvin N., Hurst C.H., Knight M.R., Teige M. and Vothknecht U.C. (2012)
A toolset of aequorin expression vectors for in planta studies of subcellular calcium concentrations in Arabidopsis thaliana.
Journal of Experimental Botany 63 (4), 1751-1761 (abstract)

Fuchs M., Vothknecht U.C. and Chigri F. (2011)
Calmodulin and Calmodulin-like proteins in Arabidopsis thaliana.
Endocytobiosis and Cell Research 21, 114-121 (abstract)

Chigri F., Flosdorff S., Pilz S., Kölle E., Dolze E., Gietl C. and Vothknecht U.C. (2011)
The Arabidopsis calmodulin-like proteins AtCML30 and AtCML3 are targeted to mitochondria and peroxisomes, respectively.
Plant Molecular Biology 78, 211–222 (abstract)

Stael S., Rocha A.G., Wimberger T., Anrather D., Vothknecht U.C. and Teige M. (2011)
Crosstalk between calcium signalling and protein phosphorylation at the thylakoid membrane.
Journal of Experimental Botany 63 (4), 1725-33 (abstract)

Stael S., Rocha A.G., Robinson A.J., Kmiecik P., Vothknecht U.C. and Teige M. (2011)
Arabidopsis calcium-binding mitochondrial carrier proteins as potential facilitators of mitochondrial ATP-import and plastid SAM-import.
FEBS Letters 585 (24), 3935–3940 (abstract)

Stael S., Wurzinger B., Mair A., Mehlmer N., Vothknecht U.C. and Teige M. (2011)
Plant organellar calcium signalling - an emerging field.
Journal of Experimental Botany 63 (4), 1525-1542 (abstract)

Vothknecht U.C., Otters S., Henning R. and Schneider D. (2011)
Vipp1: A very important protein in plastids!?
Journal of Experimental Botany 63 (4), 1699-1612 (abstract)

Mehlmer N., Sippel C., Pérez Hernández D. and Vothknecht U.C. (2011)
Brassica rapa subsp. pekinensis: a new model plant for the isolation of chloroplasts and biochemical studies.
Endocytobiosis and Cell Research 21, 53-59 (abstract)

Chigri F., Sippel C., Kolb M., and Vothknecht U.C. (2009)
Arabidopsis OBG-like GTPase (AtOBGL) is localized in chloroplasts and has an essential function in embryo development.
Molecular Plant 2 (6), 1373-1383 (abstract)

Bussemer J., Chigri F. and Vothknecht U.C. (2009)
AFG1-like protein 1 (AFG1L1) is a calmodulin-binding AAA+-ATPase with a dual localization in chloroplasts and mitochondria.
FEBS Journal 275, 3870-3880 (abstract)

Bussermer J., Vothknecht U.C. and Chigri F. (2009)
Calcium Regulation in Endosymbiotic Organelles of Plants.
Plant Signaling & Behaviours 4, 1-4 (abstract)

Kuhn S., Bussemer J., Chigri F. and Vothknecht U.C. (2009)
Calcium depletion and calmodulin inhibition affect import of nuclear-encoded proteins into plant mitochondria.
Plant Journal 58, 696-704 (abstract)

Aseeva E.,Ossenbühl F., Cho W.K., Sippel C., Stein R., Eichacker L.A., Meurer J., Wanner G., Westhoff P., Soll J. and Vothknecht U.C. (2007)
Vipp1 is required for basic thylakoid membrane formation but not for the assembly of thylakoid protein complexes.
Plant Physiol. et Biochem. 45, 119-128 (abstract)

Martin T., Sharma R., Sippel C., Waegemann K., Soll J. and Vothknecht U.C. (2006)
A protein kinase family in Arabidopsis phosphorylates chloroplast precursor proteins.
J. Biol. Chem. 281, 40216-40223 (abstract)

Chigri F., Hörmann F., Bölter B., Stamp A., Stammers D., Soll J. and Vothknecht U.C. (2006)
Calcium regulation of chloroplast protein translocation is mediated by calmodulin-binding to Tic32.
Proc. Natl. Acad. Sci. U.S.A. 103, 16051-16056 (abstract)

Chigri F., Soll J. and Vothknecht U.C. (2005)
Calcium regulation of chloroplast protein import.
Plant Journal 42, 821-831 (abstract)

Vothknecht U.C. and Soll J. (2005)
Chloroplast membrane transport: Interplay of prokaryotic and eukaryotic traits.
Gene 354, 99-109 (abstract)

Vothknecht U.C. and Soll J. (2005)
Protein Import into Chloroplasts: Who, when, and how?
In: The Structure and Function of Plastids. Wise R.R. and Hoober J.K. (eds.), Kluwer Academic Publishers, Dordrecht, pp. 53-74

Vothknecht U.C. and Soll J. (2005)
The Protein Import pathway into Chloroplasts: A single tune or variations on a common theme?
In: Plastids. Annual Plant Reviews, Vol 13. Møller S.G. (ed.), Blackwell Publishing, Oxford, pp. 157-179

Aseeva E., Ossenbühl F., Eichacker L.A., Wanner G., Soll J. and Vothknecht U.C. (2004)
Complex formation of Vipp1 depends on its alpha-helical PspA-like domain.
J. Biol. Chem. 279, 35535-35541 (abstract)

Westphal S., Soll J. and Vothknecht U.C. (2003)
Evolution of chloroplast vesicle transport.
Plant Cell Physiol. 44, 217-222 (abstract)

Vothknecht U.C. and Soll J. (2002)
Chloroplast quest: A Journey From the Cytosol into the Chloroplast and Beyond.
Rev. Physiol. Biochem. Pharmacol. 145, 181-221 (abstract)

Westphal S., Soll J. and Vothknecht U.C. (2001)
A vesicle transport system inside chloroplasts.
FEBS Letters 506, 257-261 (abstract)

Westphal S., Heins L., Soll J. and Vothknecht U.C. (2001)
Vipp1 deletion mutant of Synechocystis: A connection between bacterial phage shock and thylakoid biogenesis?.
Proc. Natl. Acad. Sci. USA 98, 4243-4248 (abstract)

Kroll D., Meierhoff K., Bechtold N., Kinoshita M., Westphal S., Vothknecht U.C., Soll J. and Westhoff P. (2001)
VIPP1, a nuclear gene of Arabidopsis thaliana essential for thylakoid membrane formation.
Proc. Natl. Acad. Sci. USA 98, 4238-4242 (abstract)

Vothknecht, U.C. and Westhoff P. (2001)
Biogenesis and Origin of Thylakoid Membranes.
Biochim. Biophys. Acta 1541, 91-101 (abstract)

Stathopoulos C., Li T., Longman R., Vothknecht U.C., Becker H.D., Ibba M. and Söll D. (2000)
One polypeptide with two aminoacyl-tRNA synthetase activities.
Science 287, 470-482 (abstract)

Vothknecht U.C. and Soll, J. (2000)
Protein import: the hitchhikers guide into chloroplasts.
Biol. Chem. 381, 887-897 (abstract)

Das R. and Vothknecht U.C. (1999)
Phenylalany-tRNA synthetase from the archaeon Methanobacterium thermoautotrophicum is an (αβ)₂ heterotetrameric protein.
Biochimie 81, 1037-1039 (abstract)

Li T., Graham D.E., Stathopoulos C., Haney P.J., Kim H.-S., Vothknecht U.C., Kitabatake M., Hong K.-W., Eggertsson G., Curnow A.W., Lin W., Celic I., Whitman W. and Söll D. (1999)
Cysteinyl-tRNA formation: the last puzzle of aminoacyl-tRNA synthesis.
FEBS Letters 462, 302-306 (abstract)

Tumbula D., Vothknecht U.C., Kim, H-S., Ibba M., Min B., Li T., Pelaschier J., Stathopoulos C., Becker H. and Söll D. (1999)
Archaeal Aminoacyl-tRNA Synthesis: Diversity replaces Dogma.
Genetics 152, 1269-1276 (abstract)

Vothknecht, U.C. and Tumbula D. (1999)
Archaea: From genomics to physiology and the origin of life.
Trends in Cell Biology 9, 159-161 (abstract)

*Kim H.-S., *Vothknecht U.C., Hedderich R., Celic I. and Söll D. (1998)
Sequence divergence of Seryl-tRNA Synthetases in Archaea.
J. Bacteriol. 180, 6446-6449 (abstract); *both authors contributed equally

Ibba, M., Morgan, S., Curnow, A.W., Pridmore, D.R., Vothknecht, U.C., Gardner, W., Lin, W., Woese, C.R. and Söll, D. (1997)
A euryarchaeal lysyl-tRNA synthetase: resemblance to class I synthetases.
Science 278, 1119-1122 (abstract)

Vothknecht U.C., Kannangara C.G. and von Wettstein D. (1997)
Barley glutamyl tRNA^Glu reductase: Mutations affecting heme inhibition and enzyme activity.
Phytochemistry 47, 513-519 (abstract)

Kannangara C.G., Vothknecht U.C., Hansson M. and von Wettstein D. (1997)
Magnesium chelatase: association with ribosomes and mutant complementation studies identify barley subunit Xantha-G as a functional counterpart of Rhodobacter subunit BchD.
Mol. Gen. Genet. 254, 85-92 (abstract)

Ibba M., Celic I., Curnow A., Kim H-s., Pelaschier J., Tumbula D., Vothknecht U., Woese C. and Söll D. (1997)
Aminoacyl-tRNA synthesis in Archaea.
Nucleic Acids Symposium Series 37, 305-306

Vothknecht U.C., Kannangara C.G. and von Wettstein D. (1996)
Expression of catalytically active barley glutamyl tRNA^Glu reductase in Escherichia coli is a fusion protein with glutathione S-transferase.
Proc. Natl. Acad. Sci. USA 93, 9287-9291 (abstract)

Vothknecht U.C. and Dörnemann D. (1995)
Charging of both, plastid tRNA^Gln and tRNA^Glu with glutamate and subsequent amidation of the misacylated tRNA^Gln by an glutamyl-tRNA amidotransferase in the unicellular green alga Scenedesmus obliquus, mutant C-2A'.
Z. Naturforsch. 50c, 789-795

Jensen P.E., Willows R.D., Larsen Petersen B., Vothknecht U.C., Stummann B.M., Kannangara C.G., Wettstein D. von and Henningsen K.W. (1995)
Three structural genes for Mg-chelatase subunits in barley : Xantha-f, -g and -h.
Mol. Gen. Genet. 250, 383-394 (abstract)

Vothknecht U.C., Willows R.D. and Kannangara C.G. (1995)
Sinefungin inhibits chlorophyll synthesis by blocking the S-adenosylmethionine: Mg-Protoporphyrin IX O-methyltransferase in greening barley leaves.
Plant Physiology and Biochemistry 33, 759-763

Willows R.D., Vothknecht U.C., Petersen B.L. and Jensen P.E. (1995)
Molecular biological and enzymatic studies confirm that xantha -f, -g and -h mutants of barley are defective in magnesium chelatase.
Barley Gen. Newsl. 24, 4-6

Vothknecht U.C., Senger H. and Dörnemann D. (1994)
Purification and partial characterization of a glutamyl-tRNA synthetase from the unicellular green alga Scenedesmus obliquus.
Planta 192, 256 - 260 (abstract)

Lehrbuch

Böttger A., Vothknecht U.C., Bolle C. and Wolf A. (2018)
Lessons on Caffeine, Cannabis & Co.
In: Learning Materials in Biosciences, 2018, p. 179-203; doi.org/10.1007/978-3-319-99546-5

Habilitationsschrift

Vothknecht U.C. (2005) Komponenten der Thylakoidbiogenese in Cyanobakterien und Chloroplasten

Invited Audio Presentations

Vothknecht U.C. (2006) Protein Import into Chloroplasts. In: Understanding Chloroplasts. Hoober J.K. (ed.), Henry Stewart Talks Ltd., London